Arterial hypertension in patients with hyperuricemia: the basis of pathogenesis, clinical significance, diagnosis, approaches to treatment

O.O. Khaniukov, Ye.D. Yehudina, O.S. Kalashnykova


The leading cause of death of hyperuricemic patients are cardiovascular diseases. The article presents a review of the literature and analysis of the mechanisms of correlation between arterial hypertension and hyperuricemia. We made the conclusion that careful blood pressure control, monitoring of target organ damage can be used as the basis for the prevention of cardiovascular diseases and the development of cardiovascular emergencies in patients with hyperuricemia. When carrying out antihypertensive therapy in such patients, it is necessary to take into account the effect of drugs on lipid and carbohydrate metabolism, the level of uric acid. The therapy should be sufficient and have high antihypertensive efficacy.


hyperuricemia; cardiovascular diseases; arterial hypertension; treatment; review


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