False controlled arterial hypertension: cognitive functions and quality of life

V.Yu. Krotova


The article presents the results of neuropsychological examination of 509 outpatients with a controlled stage II arterial hypertension and an integrated assessment of cognitive functions using the Mini-Mental State Examination and Montreal Cognitive Assessment. It was found that 32.2 % of persons with a controlled stage II arterial hypertension and a low cardiovascular risk on SCORE scale had non-dementia cognitive disorders that became the basis for considering controlled arterial hypertension in such patients with cognitive impairment as false. In patients with hypertension and cognitive disorders, based on the data on the SF-36 questionnaire, there was a significant (p < 0.001) decrease in quality of life on all sections compared to those without cognitive disorders and healthy ones. Risk factors for the development of cognitive impairment in hypertension are history of cognitive disorders in the immediate family, as well as variability of systolic blood pressure above 12 mmHg during the day according to ambulatory blood pressure monitoring and daytime diastolic blood pressure — above 10 mmHg. The results of the correlation analysis revealed a direct relationship between the deterioration in the quality of life components and impaired cognitive functions assessed by various neuropsychological tests. An early determination of the indicators of cognitive function in patients with stage II arterial hypertension as a marker of brain damage due to arterial hypertension is necessary to clarify the risk stratification for cardiovascular events.


arterial hypertension; daily blood pressure profile; cognitive functions; quality of life


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