Diuretics in the Treatment of Hypertension: are They So Bad and are All of Them Equal? Part 1

G.D. Radchenko

Abstract


This article is the first part of the literature review on the use of diuretics in the treatment of hypertension. Their antihypertensive efficacy and ability to prevent cardiovascular events are assessed. In addition, the issues on the history, classification, pharmacokinetics and pharmacodynamics of diuretics are covered. It is concluded that diuretics should be widely used for the treatment of hypertension as monotherapy or as a part of combination therapy.


Keywords


arterial hypertension; diuretics; history; classification; mechanism of action; pharmacokinetics; efficacy

References


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DOI: https://doi.org/10.22141/2224-1485.1.45.2016.74142

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