The Role of Arterial Hypertension Anamnesis and Age in Cognitive Impairment Development in Hypertensive Patients

M.Ya. Dotsenko, L.V. Herasymenko, S.S. Boev, I.O. Shekhunova

Abstract


Introduction. The role of hypertension in the development of cognitive impairment is emphasized in numerous works. Nearly all data were obtained from a group of old patients. Therefore it is of great importance to diagnose the cognitive impairment in hypertensive patients of working age beforehand. Objective. To determine the role of age and hypertensive anamnesis in the development of cognitive impairments in patients with essential hypertension of the 2nd degree. Materials and methods. We examined 102 patients with the second degree of essential hypertension, whose average age was 49.84 ± 0.83 years old. The patients were divided into 3 groups depending on their age and disease duration. A number of neuropsychological tests were used to study cognitive impairment. Results. Significant lowering of MoCA test results by 6.1 % were observed in the group of the patients older than 56 years old compared with those of the group with patients of 45 years old and younger. In the group with disease duration not more than 5 years cognitive impairments were absent. The results of MoCA test in patients with hypertensive disease duration more than 10 years were significantly less in comparison with the group of patients experienced disease up to 5 years and from 5 to 10 years in 9.9 % and in 4.9 %, respectively. Сonclusions. We have found that longer duration of the disease and older age in the patients of working age with essential hypertension of the second degree are associated with significant increase in cognitive impairment. An integral part of a comprehensive survey of hypertensive patients should be the identification of cognitive impairment.


Keywords


cognitive impairments; age; duration of arterial hypertension.

References


Murashko NK, Parnikoza TP, Chuprina GN, Sulik RV [et all.]. Algoritmprognozirovaniyarazvitiyakognitivnykhnarusheniy u bolnykh s arterialnoygipertenziey i aterosklerozomkoronarnykh i tserebralnykharteriy. [The algorithm for forecasting the development of cognitive impairment in patients with hypertension and coronary and cerebral arteries atherosclerosis]. Kiev; 2014. 40 p.Russian.

DotsenkoNYa., Boev SS., Shekhunova YA. [Arterialnaya hypertension as a risk factor in the development of cognitive impairment and issues of its secondary prevention]. Therapia. 2015; 100(7-8):9-12. Russian.

Drozdova YV, Khramtsova VV, HoncharYuA [et all.]. [Blood pressure and cognitive function in patients with hypertension in the long term after stroke]. Mezhdunarodnyiymeditsinskiyzhurnal. 2015;3: 50-54. Russian.

Petrova MM, Prokopenko SV, KoryaginaTD. [et all.]. [Cognitive impairment after stroke: origin, detection, treatment]. ConsiliumMedicum. 2014; 5: 100-104. Russian.

Smakotina SA, Trubnikova OA, AnankoYuV [et all.]. [Cognitive function and condition neurodynamics in patients with hypertension and young adulthood]. Arterialnayagipertenziya. 2007; 13(2): 145-148. Russian.

MolchanovaZhI, Sokolova AA, Anischenko LI, authors. Issledovaniekognitivnyihfunktsiy u bolnyihnevrologicheskogoprofilya: Metodicheskoeposobie[The study of cognitive function in patients with neurological profile: Toolkit]. Hantyi-Mansiysk: HMGMA; 2013. 38 p. Russian.

Parfenov VA, StarchinaYuA. [Cognitive disorders and their treatment at hypertension]. Nervnyiebolezni. 2015; 1: 16-22. Russian.

Pizova NV. [Cognitive impairments in arterial hypertension]. Meditsinskiysovet. 2015; 18: 18-21. Russian.

Pilipovich AA. [Mild cognitive impairment]. ConsiliumMedicum. 2016; 2(18): 44–49. Russian.

SirenkoYuN, author. Gipertonicheskayabolezn i arterialnyiegipertenzii[Hypertensive heart disease and arterial hypertension]. Donetsk: IzdatelskiydomZaslavskiy; 2011. 352 р. Russian.

Tabeeva GR. [Outpatient reception: cognitive impairment in patients with diabetes and hypertension]. Spravochnikpoliklinicheskogovracha. 2013; 7-8: 15-20. Russian.

Ruitenberg A, Skoog I, Ott A [et al.]. Blood pressure and risk of dementia: results from the Rotterdam study and the Gothenburg H-70 Study. Dement Geriatr. Cogn. Disord. 2001; 12(1): 33–39.

ESH/ESC 2013 Guidelines for the management of arterial hypertension. European Heart Journal. 2013; 34: 2159 – 2219.

Forette F, Seux ML, Staussen JA [et al.]. ForetteSyst-Eur study (Systolic hypertension in Europe Investigators. The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study. Arch. Intern. Med. 2002; 162 (18): 661–663.

Gelber RP, Launer LJ, White LR. The Honolulu-Asia Aging Study: epidemiologic and neuropathologic research on cognitive impairment.Curr. Alzheimer. Res. 2012; 6(9): 664-672.

Nasreddine ZS. The Montreal Cognitive Assessment (MoCA): A Brief Screening Tool For Mild Cognitive Impairment. J Am Geriatr Soc. 2005; 53: 695-699.

Randomized trial of a perendopril- bases blood pressure-lowering regimen among 6105 individuals with previous stroke or transient ischemic attack. PROGRESS collaborative group. Lancet. 2001; 358: 1033-1041.

Rockwood K, Black S, Feldman H. Progression to dementia in patients with vascular cognitive impairment without dementia: a multicentre clinical study. In: 2nd Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VasCog). Abstract book. Florence; 2005: 374-375.

Trenkwalder P. The study on Cognition and Prognosis in the Elderly (SCOPE)-recent analyses. J Hypertension. 2006; 24: 107-114.

Gorelick BP, Scuteri A, Black SE [et al.]. Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/americanstroke association. American Heart Association Stroke Council, Council on Epidemiology and Prevention, Council on Cardiovascular Nursing [et al.]. Stroke. 2011; 42(9): 2672- 2713.




DOI: https://doi.org/10.22141/2224-1485.3.47.2016.76370

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