The Role of Arterial Hypertension Anamnesis and Age in Cognitive Impairment Development in Hypertensive Patients

M.Ya. Dotsenko, L.V. Herasymenko, S.S. Boev, I.O. Shekhunova


Introduction. The role of hypertension in the development of cognitive impairment is emphasized in numerous works. Nearly all data were obtained from a group of old patients. Therefore it is of great importance to diagnose the cognitive impairment in hypertensive patients of working age beforehand. Objective. To determine the role of age and hypertensive anamnesis in the development of cognitive impairments in patients with essential hypertension of the 2nd degree. Materials and methods. We examined 102 patients with the second degree of essential hypertension, whose average age was 49.84 ± 0.83 years old. The patients were divided into 3 groups depending on their age and disease duration. A number of neuropsychological tests were used to study cognitive impairment. Results. Significant lowering of MoCA test results by 6.1 % were observed in the group of the patients older than 56 years old compared with those of the group with patients of 45 years old and younger. In the group with disease duration not more than 5 years cognitive impairments were absent. The results of MoCA test in patients with hypertensive disease duration more than 10 years were significantly less in comparison with the group of patients experienced disease up to 5 years and from 5 to 10 years in 9.9 % and in 4.9 %, respectively. Сonclusions. We have found that longer duration of the disease and older age in the patients of working age with essential hypertension of the second degree are associated with significant increase in cognitive impairment. An integral part of a comprehensive survey of hypertensive patients should be the identification of cognitive impairment.


cognitive impairments; age; duration of arterial hypertension.


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