What is the Rational Combination Antihypertensive Therapy, and Whether Remains Such the Combination of ACE Inhibitor and Diuretic?

А.Д. Радченко


This article is a review of the literature on the benefits of combination antihypertensive therapy as baseline one. There is explained the concept of rational combination. There has been discussed in detail the questions about whether the combination of angiotensin-converting enzyme (ACE) inhibitor and diuretic is rational and what diuretics and ACE inhibitors are better for long-term antihypertensive therapy.


hypertension; combination therapy; angiotensin-converting enzyme inhibitors; diuretics


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