Clinical Significance of Blood Pressure Measured in Different Ways in Patients with Hypertension

H.D. Radchenko, O.O. Torbas, Yu.M. Sіrenko

Abstract


Objective. To evaluate the presence and degree of correlation of central, office and daily blood pressure (BP) with the indicators of target organ damage. Materials and Methods. The study involved 62 patients with essential hypertension of various degrees, aged 49.6 ± 2.1 years. Results. Central systolic BP (SBP) and pulse pressure (PP) (unlike the office and daily average ones) significantly correlated with all indicators, except those which characterize the renal lesion and ancle-brachial index. The strongest relationship was with pulse wave velocity in elastic (PWVe) (r = 0.57, p < 0.001) and muscular arteries (PWVm) (r = 0.45, P < 0.001). PWVe independently correlated only with office diastolic BP (β = 4.3, P = 0.042), central SBP (β = 6.6, P = 0.05) and PP (β = 4.5, P = 0.03) and PWVm — only with central PP (β = 0.50, P < 0.001). Central PP (β = 0.40, P = 0.011; and β = 0.34, P = 0.025) was associated with intima-media thickness. Diastolic dysfunction (Е/Е′) was significantly associated only with central SBP (β = 0.55, P = 0.039).
Conclusion. BP level in the aorta has an influence on the formation of target organ damage, particularly on vessels that manifested by violations of their elastic properties, or thickening of the intima-media.


Keywords


hypertension; central blood pressure; target organs

References


2013 ESH/ESC Task Force for the Management of Arterial Hypertension. 2013 Practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC): ESH/ESC Task Force for the Management of Arterial Hypertension // J. Hypertens. — 2013 Oct. — 31(10). — 1925-1938.

A new equation to estimate glomerular filtration rate / Levey A.S., Stevens L.A., Schmid C.H., Zhang Y.L., Castro A.F. 3rd, Feldman H.I., Kusek J.W., Eggers P., Van Lente F., Greene T., Coresh J.; CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) // Ann. Intern. Med. — 2009 May 5. — 150(9). — 604-12.

Ambulatory blood pressure monitoring in clinical trials / Staessen J., Fagard R., Lijnen P., Thijs L., van Hoof R., Amery A. // J. Hypertens. Suppl. — 1991 Jan. — 9(1). — S13-9.

Arterial stiffness and arterial wave reflections are associated with systolicand diastolic function in patients with normal ejection fraction / Weber T., O’Rourke M.F., Ammer M., Kvas E., Punzengruber C., Eber B. // Am. J. Hypertens. — 2008 Nov. — 21(11). — 1194­202. doi: 10.1038/ajh.2008.277. Epub 2008 Sep 11.

Arterial stiffness/central hemodynamics, renal function, and development of hypertension over the short term / Tomiyama H., Townsend R.R., Matsumoto C., Kimura K., Odaira M., Yoshida M., Shiina K., Yamashina A. // J. Hypertens. — 2014 Jan. — 32(1). — 90-9. doi: 10.1097/HJH.0b013e3283658e7d.

Clinical trials with ambulatory blood pressure monitoring: fewer patients needed? Syst-Eur Investigators / Staessen J.A., Thijs L., Mancia G., Parati G., O’Brien E.T. // Lancet. — 1994 Dec 3. — 344(8936). — 1552-6.

Evaluation of the radial artery applanation tonometry techno-logy for continuous noninvasive blood pressure monitoring compared with central aortic blood pressure measurements in patients with multiple organ dysfunction syndrome / Meidert A.S., Huber W., Hapfelmeier A., Schцfthaler M., Mьller J.N., Langwieser N., Wagner J.Y., Schmid R.M., Saugel B. // J. Crit. Care. — 2013 Dec. — 28(6). — 908-12. doi: 10.1016/j.jcrc.2013.06.012. Epub 2013 Aug 1.

Foppa M. Echocardiography-based left ventricular mass estimation. How should we define hypertrophy? / Foppa M., Duncan B., Rohde L. // Cardiovasc. Ultrasound. — 2005 Jun 17. — 3. — 17.

Gуmez-Marcos M.A. Central blood pressure and pulse wave velocity: relationship to target organ damage and cardiovascular morbidity-mortality in diabetic patients or metabolic syndrome. An observational prospective study. LOD-DIABETES study protocol / Gуmez-Marcos M.A., Recio-Rodrнguez J.I., Rodrнguez-Sбnchez E. // BMC Public Health. — 2010 Mar 18. — 10. — 143. doi: 10.1186/1471-2458-10-143.

Mechanism(s) of selective systolic blood pressure reduction after a low-dose combination of perindopril/indapamide in hypertensive subjects: comparison with atenolol / London G.M., Asmar R.G., O’Rourke M.F., Safar M.E., on behalf of the REASON Project Investigators // J. Am. Coll. Cardiol. — 2004. — 43. — 92-99.

Relations of central and brachial blood pressure to left ventri-

cular hypertrophy and geometry: the Strong Heart Study / Roman M.J., Okin P.M., Kizer J.R., Lee E.T., Howard B.V., Devereux R.B. // J. Hypertens. — 2010 Feb. — 28(2). — 384-8.

Selective reduction of cardiac mass and central blood pressure on low-dose combination perindopril/indapamide in hypertensive subjects / de Luca N., Asmar R.G., London G.M., O’Rourke M.F., Safar M.E.; REASON Project Investigators // J. Hypertens. — 2004. — 22. — 1623-1630.

Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovas- cular disease risk: a consensus statement from the American Society of Echocardiography carotid intima-media thickness task force endorsed by the society of vascular medicine / Stein J.H., Korcarz C.E., Hurst R.T., Lonn E., Kendall C.B., Mohler E.R., Najjar S.S., Rembold C.M., Post W.S.; American Society of Echocardiography Carotid Intima-Media Thickness Task Force // J. Am. Society Echoc. — 2008. — Vol. 21 (2). — P. 93-111.

Verdecchia P. Clinical usefulness of ambulatory blood pressure monitoring / Verdecchia P., Angeli F., Gattobigio R. // J. Am. Soc. Nephrol. — 2008. — 15, Suppl. 1. — S30-3. PMID 14684668. Retrieved 2008-12-01.

White W. Blood pressure monitoring in Cardiovascular Medicine and Therapeutics. — N. Jersy: Humana Press, 2001. — 308 p.

Williams B. Anglo-Scandinavian Cardiac Outcomes Trial / The Conduit Artery Functional Endpoint (CAFE) study in ASCOT. / Williams B., O’Rourke M. // J. Hum. Hypertens. — 2001 Aug. — 15, Suppl. 1. — S69-73.

Wittenberg C.K. Systolic hypertension therapy trial begins // JAMA. — 1985. — 253. — 1700-1701.




DOI: https://doi.org/10.22141/2224-1485.5.37.2014.82748

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