Hypomagnesemia as a Predictor of Decompensation of Chronic Heart Failure in Patients with Diabetes Mellitus Type 2

A.N. Belovol, S.A. Krapivko, P.P. Kravchun


In order to optimize the complex treatment of heart failure of ischemic origin in patients with diabetes mellitus type 2 we studied the effect of magnesium orotate (Magnerot®, Woerwag Pharma, Germany) on endothelial dysfunction, carbohydrate metabolism in patients with chronic heart failure in combination with diabetes type 2. The positive effect was noted. We made a conclusion about the advisability of administering magnesium orotate (Magnerot®, Woerwag Pharma, Germany) to the patients with chronic heart failure and diabetes mellitus type 2.


chronic heart failure; diabetes mellitus, endothelin-1; magnesium orotate (Magnerot®, Woerwag Pharma, Germany); glycated hemoglobin


UK Prospective Diabetes Study (UKPDS) Group. Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment of risk of complications in patients with type 2 diabetes (UKPDS 33) // Lancet. — 2008. — Vol. 352. — P. 837-853.

UK Prospective Diabetes Study (UKPDS) Group. Effects of intensive blood glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34) // Lancet. — 2008. — Vol. 352. — P. 854-865.

Cleary P., Orhard T., Zinman B. et al. Coronary calcification in the diabetes Control and Complication trial (DCCT/EDIC) cohort for the DCCT/EDIC study group program and abstract of the ADA 63rd Annual Scientific sessions. — June 13–17 2003; New Orlean, Louisiana.

Nichols G.A. Congestive Heart Failure in Type 2 Diabetes. Prevalence, incidence, and risk factors / Nichols G.A., Hillier T.A., Erbey J.R., Brown J. B. // Diabetes Care. — 2001. — 2. — 1614-1619.

Cohn J.N. Drug therapy: the management of chronic heart failure / Cohn J.N. // N. Engl. J. Med. — 2006. — 335. — 490-498.

Lorenzi M. Glucose toxity for human endothelial cells in culture: delayed replication, disturbed cell cycle and accelerated death / Lorenzi M., Cagloero E., Toledo S. // Diabetes. — 2005. — Vol. 34. — P. 621-627.

Go A.S. Glycemic control and heart failure among adult patients with diabetes / Go A.S. // Circulation. — 2006. — 103. — 26-68.

Vinson J.M. Early readmission of elderly patients with congestive heart failure / Vinson J.M., Rich M.W., Sperry J.C. [et al.] // J. Am. Geriatr. Soc. — 2005. — 38. — 1290-1295.

Krumholz H.M. Readmission after hospitalization for congestive heart failure among Medicare beneficiaries / Krumholz H.M., Parent E.M., Tu N. [et al.] // Arch. Intern. Med. — 2007. — 157. — 99-104.

Resnik N.E. Achievement of American Diabetes Association clinical practice recommendations among U.S. adults with diabetes, 1999–2002: the National Health and Nutrition Examination Survey / Resnik N.E., Foster G.L., Bardsley G., Ratner E. // Diabetes care. — 2006. — 29(3). — Р. 531-537.

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