Do We Always Prescribe Life-Saving Medicines to Our Patients, or Indications for Statin Therapy and Statin Administration in Actual Practice (Based on the СИСТЕМА Study)

V.I. Tseluiko


The article presents the results of the СИСТЕМА study, which analyzed the prescriptions of statins to the patients with hypertension, who sought help from a cardiologist in the out-patient hospital. It was found that in actual clinical practice, there is an underestimation of the risk for the patient by doctors and the possibility to improve prognosis ­using statins. Most often, but less frequently than they should, cardiologists prescribe statins to the patients with myocardial infarction. In the presents of a history of stroke, diabetes mellitus, chronic kidney disease or high blood pressure, statins are being prescribed by a cardiologist in less than half of the patients.


statins; arterial hypertension; office blood pressure; lipid-lowering therapy


CCT Collaboration // Lancet. — 2015. — 385. — 1397-405.

Taylor F., Ward K., Moore T.H. et al. // Cochrane Database Syst. Rev. — 2011. — 1. — CD004816.

Colhoun H.M., Betteridge D.J., Durrington P.N. et al. Оn behalf of the CARDS investigators. Primary prevention of cardiovascular desease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicenter randomized placebo-controlled trial // Lancet. — 2004. — 364. — 685-96.

Athyros V.G., Mikhailidis D.P., Papageorgiou A.A. et al. The effect of statins versus untreated dyslipidaemia on renal function in patients with coronary heart disease. A subgroup analysis of the Greek atorvastatin and coronary heart disease evaluation (GREACE) study // J. Clin. Pathol. — 2004. — 57(7). — 728-734.

Коваленко В.М. Проблеми здоров’я і медичної допомоги та модель покращення в сучасних умовах: Посібник. — К., 2016.

Лапач С.Н., Чубенко А.В., Бабич П.Н. Статистические методы в медико-биологических исследованиях с использованием Exel. — К.: Морион, 2001.

Stone N.J. et al. 2013 ACC/AHA Blood Cholesterol Guideline.

Catapano et al. 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias // European Heart Journal. — 2016.

Стабільна ішемічна хвороба серця: Адаптована клінічна настанова, заснована на доказах. — 2016.

Scandinavian Simvastatin Survival Study Group. Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S) // Lancet. — 1994. — 344. — 1383-1389.

American Diabetes Association. Standards of Medical Care in Diabetes — 2016 // The Journal оf Clinical аnd Applied Research аnd Education. — 2016.

Am. J. Kidney Dis. — 2002. — 39(2 suppl. 1). — 818.

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