New possibilities in the treatment of pulmonary arterial and chronic thromboembolic pulmonary hypertension in Ukraine

Authors

  • G.D. Radchenko Scientific and Consultative Expert Center for Pulmonary Hypertension, State Institution “National Scientific Center “M.D. Strazhesko Institute of Cardiology” of the National Academy of Medical Sciences of Ukraine”, Kyiv, Ukraine

DOI:

https://doi.org/10.22141/2224-1485.6.62.2018.153931

Keywords:

pulmonary hypertension, specific therapy, endothelin receptor blockers, bosentan

Abstract

The aim of this paper is the review of literature data about effectiveness and safety of bosentan in the treatment of pulmonary hypertension. In addition, it considers some aspects of diagnosis, classification and pathogenesis of pulmonary hypertension. It is concluded that bosentan is effective both as monotherapy and in combination therapy of patients with pulmonary arterial hypertension. In patients with chronic thromboembolic pulmonary hypertension, it is possible to use bosentan, but positive changes are less significant than in patients with pulmonary arterial hypertension. Data about possible adverse effects of bosentan and ways to avoid them are considered.

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Published

2021-09-27

How to Cite

Radchenko, G. (2021). New possibilities in the treatment of pulmonary arterial and chronic thromboembolic pulmonary hypertension in Ukraine. HYPERTENSION, (6.62), 43–56. https://doi.org/10.22141/2224-1485.6.62.2018.153931

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Review

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